From “Your Next Move” by Michael D. Watkins in the section of Core promotion challenges:

What's really changed? What should you do?
Broader impact horizon: There is a broader range of issues, people, and ideas to focus on. Balance depth and breadth
Greater complexity and ambiguity: There are more variables, and there is greater uncertainty about outcomes. Delegate more deeply.
Tougher organization politics: There are more powerful stakeholders to contend with. Influence differently.
Further from the front lines: There is greater distance between you and the people executing on the ground, potentially weakening communication and adding more filters. Communicate more formally.
More scrutiny: There is more attention paid to your actions by more people, more frequently. Adjust to greater visibility.